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Allergies

 
     
     
 

  Allergies are a seasonal headache for nearly 50 million Americans* with approximately 16.7 million office visits to health care providers each year attributed to allergic rhinitis ( nasal symptoms caused by allergies). 

Allergies are caused by a reaction of the immune system to a substance ( cat dander, pollen, dust mites, etc.) in the environment that is usually harmless to most people. Over time, susceptible individuals develop a sensitivity to one of these substances. Once this happens allergy symptoms will usually recur every time there is sufficient re-exposure to the same substance. Because allergies are the result of repeated exposure, a person can develop allergies at any age. Contrary to popular opinion you can get allergies for the first time as an adult, in fact this is very common.  

When most people think of allergy symptoms they think of sneezing, runny nose, and watery eyes. While these symptoms are common, allergies can cause many other symptoms. Nasal congestion, cough, headache, pain around the eyes, and even fatigue can be common symptoms in many people. Someone with allergies can have all of the above symptoms or a few or just one. This wide variation in symptoms is why people and their doctors sometimes don't think of allergies or confuse allergy symptoms with a cold.

Cold and allergy symptoms overlap a lot. Below is a list of some of the differences between allergies and colds.

  • There is no fever and no muscle ache with allergies
  • Itchiness in nose, ears, and throat (especially the palate or roof of the mouth) is present in allergies
  • Symptoms of seasonal allergies usually last longer than the typical duration of a cold, which is usually 7 to 10 days.

 

So now I have allergies. What should I do?

There's actually quite a bit you can do to relieve your symptoms. Unfortunately most allergies are due to substances that are not easily removed from our environment like pollen and dust. You can try to minimize your exposure by staying indoors in air conditioned rooms on days with high pollen counts. Dust or more accurately Dust Mite allergies are a problem all year round, but are worse in the winter months. This is because dust mites are microscopic animals that live in our bedding and feed on dead skin cells. When they die, their bodies become part of the dust in the air and we inhale them. In the winter when the air is very dry we shed more skin cells, in addition, the dust in our home becomes airborne more easily. There are much higher concentrations of these in our beds and pillows than anywhere else in the house. Sometimes sealing the bedding with a special cover can reduce the amount of dust mite allergens we ultimately inhale.

Medications:   There are four main categories of medication that can help allergy sufferers

  • Antihistamines - sedating vs. nonsedating
  • Decongestants
  • Nasal Sprays - Decongestant sprays, and corticosteriod sprays
  • Leukotriene inhibitors

 

1) Antihistamines - There are two types of antihistamines those which cause sedation and those which don't. 

 

 

 

Antihistamines work by blocking the effects of a substance called histamine. Histamine is produced by the body in response to an allergic reaction. It has several effects on the tissues in the body. The end result is the production of symptoms associated with allergies.

 

Sedating - i.e. Benadryl ( diphenhydramine), Chlortrimaton, and most over the counter drugs except Claritin. Most other over the counter allergy medications that are "non drowsy" have pseudoephedrine added to them to try and counteract the effects of the antihistamine, but this usually doesn't work.

Non-sedating - Clarinex, Claritin ( Loratadine), and Allegra are the only true non-sedating antihistamines. Clarinex and Allegra require a prescription while Loratadine is now available over the counter

 

2) Decongestants - Nearly all decongestants have the same ingredient - pseudoephedrine

 Whether you take Actifed, Tylenol sinus, Sudafed or Claritin-D ( the D stands for decongestant), they all have pseudoephedrine in them. Pseudoephedrine works by causing constriction of blood vessels throughout the body. In the nasal tissues, this constriction causes the tissues to shrink and opens up the airways. Some people have a hard time  tolerating these medications because they make them feel "racey" or "hyper".  Pseudoephedrine can also cause insomnia and can raise blood pressure or cause rapid or irregular heart beat.

 

3) Nasal Sprays - These also can be broken down in to two types. Nasal decongestant sprays and Nasal corticosteroids

Nasal Decongestant Spray - Afrin, Neo-Synephrine and similar over the counter sprays which contain oxymetazoline or phenylephrine work by constricting the blood vessels in the nasal tissues and shrinking them. They can be very effective for short term use, but after even a few days the body can become " dependant" on this medication. When you stop these sprays after prolonged use you may go through a period of rebound where you have more severe congestion than you had before you started the spray. 

Nasal Corticosteroids - These medications are completely different than the over the counter sprays. They all require a prescription and all contain some form of "cortizone like" medication as their active ingredient. The active ingredients in these medications are targeted at the underlying problem - the inflammation, which is the hallmark of allergic reactions. They don't work as fast as decongestant sprays, but they can be used for prolonged periods of time without any risk of dependency. Examples of these drugs are Flonase, Nasacort AQ, Nasonex, Nasarel, Vancenase, and others.

4) Leukotriene Inhibitors - Leukotrienes are something most people have never heard of. They are another type of inflammatory substance that the body makes and they are involved in allergies and asthma. There is only one drug in this class currently. It is called Singulair. Singulair was originally developed for the treatment of asthma and has been around for several years. It was recently approved for use in the treatment of allergies. It has several advantages over antihistamines. One significant advantage is that it can be used in men with enlarged prostates who can't take most antihistamines.

 

 

* National Institute of Allergy and Infectious Diseases web site